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itwiki Encefalite letargica; nlwiki Encephalitis lethargica; plwiki Zapalenie mózgu von Economo; ptwiki Encefalite letárgica; ruwiki Летаргический энцефалит. Date, Source, von Economo C. Die Encephalitis lethargica (Mit zwölf lithographischen Tafeln). Franz Deuticke, ss. Leipzig-Wien. Translation for ‘encefalite letargica’ in the free Italian-English dictionary and many other English translations.

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Inin a substantial Oxford University Press compendium reviewing the historic and contemporary views on EL, its editor, Joel VIlensky of the Indiana University School of Medicine, quotes Pool, writing inwho states, “we must confess that etiology is still obscure, the causative agent still unknown, the pathological riddle still unsolved…”, and goes on to offer the following conclusion, as letaggica that publication date:.

Sheffield was perhaps the city hardest hit by EL in England, particularly during the great epidemic ofso that there was no shortage of case material upon which Hall could base his conclusion that neither in the acute nor in the chronic phase of the disorder was there a degree of similarity with influenza which would confuse a careful physician.

In some places the peak of influenza measured by reported mortality anticipates that of encephalitis reported cases by many weeks, as in London, while in others, as in Manchester, encephalitis begins to wane before influenza reaches its highest point. Economo believed that the EL pathogen accessed the body ecnefalite the airways, but, in contrast to influenza, did not propagate thence into the lower respiratory organs.

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After the disorder was gradually forgotten by the medical community, but it survived in the memories of those who had experienced it; Economo, for example, was reminded by his initial EL cases of tales of the nona related by his grandmother.

Johann Ambrosius Barth; Leipzig: Author manuscript; available in PMC Oct 1. Learn how and when to remove these template messages. Thesis, Kiel Karl J. Particularly significant is that EL cases were reported in numbers before pandemic influenza cast its shade over Europe. Evans AC, Freeman W. Studies on the etiology of epidemic encephalitis.


This approach, however, is rendered impractical by inherent difficulties in estimating case numbers of these diseases. Constantin von Economo Substantia nigra. In ten the result was totally negative, in five cases streptococci could be cultivated, which the bacteriological institute identified as small gram-positive diplostreptococci … In these same cases … streptococci could be demonstrated … in the subarachnoid fluid, the ventricle contents and … within vascular infiltrates and between the ependymal cells on the floorof the 4th ventricle.

Berger W, Untersteiner R. Preludes and NocturnesSandman: Similarly, the course of the major British epidemic ofthe greatest single outbreak in the history of EL, was not paralleled by changes in influenza statistics:. Foerster O, Wilmanns K, editors. December Learn how and when to remove this template message. Many of those who survived never returned to their pre-existing “aliveness”. Travel Med Infect Dis. Among the most extensive was that of Karl Friedrich Baer, who in analyzed data for EL patients: This was perhaps the major reason influenza declined as an explanation for EL towards the end of the s.

The only specific link between this curiosity and EL was the deep somnolence which drew puzzled attention, and even this similarity was more misleading than enlightening: A brief description of the disease, with short notes on the postencephalitic lethargic cases treated at the Banchi Indian mental hospital. These authors also remarked that EL differed from influenza in that no major organ, apart from the brain and respiratory tract, were significantly affected Siegmund Dobreff M, Saprjanoff T.

Doll’s House, and Sandman Vol.

Ilnona o encefalite lletargica epidemica. Comparative severity of influenza and EL epidemics Further, there was no recognizable correlation between the relative impacts of EL and influenza in particular countries or regions.

The published medical literature was limited to a few cases; official circles dismissed it entirely. Age and gender The preferred age of onset by EL did not vary significantly throughout the s, with those aged 12 letagica 35 years most at risk.


Grosz K, Pappenheim M. No recurrence of the epidemic has since been reported, though isolated cases continue to occur. Die Influenza und das Letarfica. Public domain Public domain false false. Some lethargic patients state that during the whole time that they were supposed to be asleep that they could hear everything that was going on around, but could not rouse themselves. Somnolence was initially regarded as the primary symptom of EL, but extreme sleepiness could also accompany influenza.

Encephalitis lethargica

The role of influenza in the etiology of EL was vigorously debated until Degenerative SA Friedreich’s ataxia Ataxia-telangiectasia. Others isolated a variety of cocci, but could not be enecfalite that their presence was not the encefaljte of secondary infection Ribbert ; Parsons See other articles in PMC that cite the published article.

Mentioned as potential disease vector in Darci Stone’s award-winning short story Mara’s Shadow. Prevalence of encephalitis epidemica in China. Finally, influenza played no favorites with respect to genderbut it was widely reported that there were up to twice as many male as female EL cases, although the prognosis in the latter tended to be worse Stern Views Read Edit View history. Wien Arch Inn Med.

The reporting of such symptoms might also occur in response to letartica from the physician, as in this EL case:. Leyden E, Guttmann S, editors. Influenza was a very public invader, while EL was much stealthier; those who contracted influenza generally returned to full health within months, whereas survival of the acute phase of EL was often the segue to life-long debility. In the first, the distributions of influenza-pneumonia deaths by month of death and of EL deaths by month of illness onset in Seattle-King Letsrgica northwest USA between and were compared.